pentobarbital will decrease the level or effect of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Bildskärm Closely. Double brexpiprazole dose over 1-2 weeks if administered with a strong CYP3A4 inducer.pentobarbital decreases levels of panobinostat ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. … Read More